Contents:
How to Use Hibiclens
How to Use Hibistat
Hibiclens Safety and Warnings
Hibistat Warnings
Laundry Information

Hibiclens:

Skin wound and general skin cleansing:
Thoroughly rinse the area to be cleansed with water. Apply the minimal amount of HIBICLENS necessary to cover skin or wound and wash gently. Rinse thoroughly.

Personnel hand wash:
Wet hands with water. Dispense 5ml of HIBICLENS into cupped hands and wash in a vigorous manner for 15 seconds. Rinse and dry thoroughly.

Surgical hand scrub:
Wet hand and forearms with water. Scrub for 3 minutes with 5ml of HIBICLENS and a wet brush. Rinse thoroughly under running water. Repeat. Dry thoroughly.

Preoperative skin preparation:
Apply HIBICLENS liberally to surgical site and swab for at least 2 minutes. Dry with a sterile towel. Repeat. Dry with a sterile towel.

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Hibistat:

Rub hands vigorously with HIBISTAT Towelette for approximately 15 seconds, paying particular attention to nails and inter-digital spaces. HIBISTAT dries rapidly in use. The emollients contained in the HIBISTAT Towelette protects the hands from the potential drying effect of alcohol. No water or towel drying is necessary.

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Hibiclens Safety & Warnings:

SAFETY

The extensive use of chlorhexidine gluconate for over 20 years outside the United States has produced no evidence of absorption of the compound through intact skin. The potential for producing skin reactions is extremely low. HIBICLENS can be used many times a day without causing irritation, dryness, or discomfort.

WARNINGS

FOR EXTERNAL USE ONLY. KEEP OUT OF EYES, EARS AND MOUTH. HIBICLENS SHOULD NOT BE USED AS A PREOPERATIVE SKIN PREPARATION OF THE FACE OR HEAD. MISUSE OF HIBICLENS HAVE BEEN REPORTED TO CAUSE SERIOUS AND PERMANENT EYE INJURY WHEN IT HAS BEEN PERMITTED TO ENTER AND REMAIN IN THE EYE DURING SURGICAL PROCEDURES. IF HIBICLENS SHOULD CONTACT THESE AREAS, RINSE OUT PROMPTLY AND THOROUGHLY WITH WATER.

Avoid contact with meninges. HIBICLENS should not be used by persons who have a sensitivity to it or its components. Chlorhexidine gluconate has been reported to cause deafness when instilled in the middle ear through perforated eardrums. Irritation, sensitization, and generalized allergic reactions have been reported with chlorhexidine-containing products, especially in the genital areas. If adverse reactions occur, discontinue use immediately and if severe, contact a physician. Keep this and all drugs out of the reach of children. In case of accidental ingestion, seek professional assistance or contact a Poison Control Center immediately.

Accidental ingestion: Chlorhexidine gluconate taken orally is poorly absorbed. Treat with gastric lavage using milk, egg white, gelatin or mild soap. Employ supportive measures as appropriate. Avoid excessive heat (above 104°F).

For more information, call 800.843.8497

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Hibistat Warnings:

WARNINGS

FOR EXTERNAL USE ONLY. KEEP OUT OF EYES, EARS AND MOUTH. HIBISTAT SHOULD NOT BE USED AS A PREOPERATIVE SKIN PREPARATION OF THE FACE OR HEAD. MISUSE OF CHLORHEXIDINE-CONTAINING PRODUCTS HAS BEEN REPORTED TO CAUSE SERIOUS AND PERMANENT EYE INJURY WHEN IT HAS BEEN PERMITTED TO ENTER AND REMAIN IN THE EYE DURING SURGICAL PROCEDURES. IF HIBISTAT SHOULD CONTACT THESE AREAS, RINSE OUT PROMPTLY AND THOROUGHLY WITH WATER.

Avoid contact with meninges. HIBISTAT should not be used by persons who have a sensitivity to it or its components. Chlorhexidine gluconate has been reported to cause deafness when instilled in the middle ear through perforated eardrums. Irritation, sensitization, and generalized allergic reactions have been reported with chlorhexidine-containing products especially in the genital areas. If adverse reactions occur, discontinue use immediately and if severe, contact a physician. Keep this and all drugs out of the reach of children. In case of accidental ingestion, seek professional assistance or contact a Poison Control Center immediately. Avoid excessive heat (above 104ºF)

Warning flammable. This product is alcohol based. Alcohol is extremely flammable. It should be kept away from flame or devices which may generate an electrical spark.

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Laundry Information:

IMPORTANT LAUNDERING ADVICE FOR HOSPITAL STAFF AND OTHER USERS OF ANTISEPTIC PATIENT SKIN PREPARATIONS CONTAINING CHLORHEXIDINE GLUCONATE

Chlorhexidine gluconate is a unique agent that closely fits the definition of an ideal antimicrobial agent, having (among others) one of the most important characteristics of persistent activity. This persistence is due to chlorhexidine gluconate binding to the protein of the skin and, thus, being available for residual activity over a relatively long period of time. Chlorhexidine gluconate, however, binds not only to protein of the skin, but also to many fabrics, particularly cotton. Thus, special laundering procedures should be considered when such products contact these fabrics. As a result of such contact, chlorhexidine gluconate may become adsorbed onto the fabric and not be removed by washing. If sufficient available chlorine is present during the washing procedure, a fast brown stain may develop due to a chemical reaction between chlorhexidine gluconate and chlorine.

SUGGESTED LAUNDERING PROCEDURES TO LIMIT STAINING

1. Not Aging. Avoid allowing the product to age (set) on unwashed linens.

2. Flushing and Washing. A flush operation as the initial step in the wash process is helpful in the laundering of linen exposed to chlorhexidine gluconate. Such flushing is also important in the laundering of linen which contains organic materials such as blood or pus. For best results, warm water flushes (90°-100°F) are recommended. After a number of initial flushings followed by a washing with a low alkaline/non-chlorine detergent, most articles which come in contact with chlorhexidine gluconate should have an acceptable level of whiteness. If a rewash process using bleach is necessary to achieve a greater degree of whiteness, the bleach used should be non-chlorine bleach.

3. Not Using Chlorine Bleach. Modern laundering methods often make the use of chlorine bleach unnecessary. It is worthwhile trying to wash without chlorine to ascertain if the resulting degree of whiteness is acceptable. Omission of chlorine from the laundering process can extend the useful life of cotton articles since oxidizing bleaches such as chlorine may cause some damage to cellulose even when used in low concentration.

4. Changing to a Peroxide-Type Bleach, Such as Sodium Perborate, Sodium Percarbonate or Hydrogen Peroxide. This should eliminate the reaction that could occur with the use of chlorine bleaches. If a chlorine bleach must be used, a concentration of less than 7 ppm available chlorine (1/10 the normal bleach level) is suggested to minimize possible staining.

A NOTE ON LAUNDERING OF PERSONAL CLOTHING

The laundering procedures set forth above using low alkaline, non-chlorinated laundry detergents are also applicable to laundering of uniforms and lab coats. Commercially available laundry detergents that do not contain chlorine include Borax, Borateem, Dreft, Oxydol, and Ivory Snow. These products, however, will not remove stains previously set into the fabric.

RECLAMATION OF STAINED LINENS

For those linens which previously have been stained due to the chemical reaction between chlorhexidine gluconate and chlorine, the following laundering procedure may be helpful in reducing the visible stain:

Operation	Water Level	Temperature	Time (Min)	Supplies/100 lb
Break	Low	180°F	20	1.5 lb oxalic acid
Flush	High	Cold	1	--------
Emulsify	Low	160°F	5	18 oz emulsifier
Flush	High	Cold	1	--------
Bleach	Low	180°F	20	2 lb alkali builder and 1 lb organic bleach
Rinse	High	Cold	1	--------
Antichlor	High	Cold	2	4 oz antichlor
Rinse	High	Cold	1	--------
Rinse	High	Cold	1	--------
Sour	Low	Cold	4	2 oz rust removing sour

For more information, call 800.843.8497

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